No, the shot does not protect against sexually transmitted infections (STIs). The best way to prevent STIs if you’re having sex is using a condom or internal condom. Dental dams, gloves, some vaccines (HPV and hepatitis B vaccines) and daily medications, such as PrEP for the prevention of HIV also offer STI protection. If you’re concerned about both pregnancy and STIs, doubling up with the shot and condoms is a great option.
In-office shot (Depo-Provera)

Does the shot protect against STIs?
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Will birth control make me gain weight?
Most birth control methods will not cause weight gain. Everyone’s body responds to birth control differently, but research shows that the pill, patch, the hormonal IUD, the ring, and non-hormonal birth control methods like a copper IUD or condoms don’t cause weight gain (or loss). Studies do show that about 1 in 4 people who use the shot will gain some weight (around 5% of body weight).
How can birth control help an ovarian cyst?
One of the main ways hormonal birth control prevents pregnancy is by stopping ovulation—meaning that the egg never leaves the ovary. The pill, the patch, the ring, and the shot are the methods that are the most reliable at blocking ovulation, so people using these methods may have fewer ovarian cysts. If you tend to get ovarian cysts, your provider may recommend one of these methods to prevent future cysts. The progestin-only pill, also called the mini-pill, has an unpredictable effect on ovulation and may actually lead to more cysts. These cysts almost always disappear on their own, but if you’ve had problems with cysts in the past, the mini-pill may not be the best birth control for you.
What's an ovarian cyst?
A cyst is basically a bubble—a collection of fluid with a thin wall around it. Functional cysts are formed when a follicle (the fluid-filled sac that develops around an egg during ovulation) grows larger than expected. Sometimes they can cause un-fun symptoms like abdominal discomfort, pelvic pain, pain during bowel movements, or pain during sex. Most cysts disappear on their own, but if they keep growing they can cause severe pelvic pain or pain that causes dizziness or fainting and comes with a fever or vomiting. If you have any of these severe symptoms, go see your health care provider ASAP. Some hormonal birth control methods—the ones that work by blocking ovulation—may mean fewer ovarian cysts. If you tend to get cysts, your provider might recommend you try a method like the pill, the ring, the patch, or the shot.
What should I do before stopping my birth control?
If you’d like to stop your birth control and try to get pregnant, here’s some information about returning to fertility after using different methods of birth control.
If you’re just not vibing with your choice of birth control, it might be time to switch things up! But before you do, it’s important to take a second to ask yourself some questions to make sure you’re ready. Thinking about why you want to switch methods and what your needs are going forward will help you and your health care provider plan your next steps.
If you’d like to stop your birth control and try to get pregnant, here’s some information about returning to fertility after using different methods of birth control.
Can ibuprofen help reduce heavy periods and irregular bleeding?
Yes. Ibuprofen and other NSAIDs, like naproxen, can decrease menstrual flow and cramping. So if you have heavy or painful periods, your health care provider may recommend taking ibuprofen to help reduce heavy flow and/or cramping. It can also help reduce the irregular bleeding that is sometimes a side effect of progestin-only birth control methods like the shot or the implant.
Is there a birth control that’s drunk-hookup ready?
And speaking of covering all your bases, here are some tips for safer, smarter hookups.
If you’re under the influence of alcohol—or anything else—a birth control method that doesn’t require action right when you’re about to get your freak on may be your safest bet. Fortunately, there are plenty of options. Note: These methods will cover you against pregnancy, but you should pair them with a condom for STI protection.
And speaking of covering all your bases, here are some tips for safer, smarter hookups.
Is it normal to get headaches from the shot?
Headaches are pretty uncommon with the shot, so you might want to look into other reasons for the aching. If the headaches are bad, definitely go see your doctor.
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How soon can I get pregnant after going off the shot?
If you’re already on Depo and you’ve decided you want to get pregnant, you’re going to have to wait it out. There’s no way around it. But 12 weeks after your last injection, you’ll be ready to start trying. It may take some time, though. Sometimes it can take up to 10 months after the last shot for fertility to come back completely.
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How often do I have to get the shot?
You have to get the shot every 3 months from a healthcare provider. That’s only 4 times a year!
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Is it safe to lose blood by spotting a lot?
Spotting, which can happen with a bunch of different methods, doesn’t make you lose that much blood, even though it might seem like it. We have a Provider Perspective article about it if you want to learn more.

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